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Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Type of registration
Retrospectively registered

Titles & IDs
Public title
Psychotherapy for depression: a comparison of two cognitive treatments
Scientific title
A randomised trial of cognitive behaviour therapy and schema focused therapy in major depression to reduce depressive symptoms over six months.
Secondary ID [1] 290420 0
Nil known
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Depression 874 0
Condition category
Condition code
Mental Health 942 942 0 0

Study type
Description of intervention(s) / exposure
Cognitive Behaviour Therapy (CBT) versus Schema Focused Therapy (SFT).
Duration: 12 months.
Intervention code [1] 657 0
Treatment: Other
Intervention code [2] 296254 0
Comparator / control treatment
Control group

Primary outcome [1] 1238 0
To test the hypothesis that SFT is superior to CBT in achieving sustained change in depression as judged by independent clinician ratings (MADRS)
Timepoint [1] 1238 0
Over the last 6 months of treatment.
Secondary outcome [1] 2256 0
i) To compare SFT with CBT on i) Outcomes
Timepoint [1] 2256 0
At the end of the weekly sessions.
Secondary outcome [2] 2257 0
ii) Sustained change on a self-report measure (BDI-II) of depressive symptoms
Timepoint [2] 2257 0
Secondary outcome [3] 2258 0
iii) Remission (MADRS & BDI-II<10 for 2 weeks) and recovery (MADRS & BDI-II<10 for 8 weeks).
Timepoint [3] 2258 0
At the end of weekly sessions and during the following monthly sessions.

Key inclusion criteria
Individuals currently experiencing a major depressive episode (DSM-IV). All people accepted into the study need to be free of any centrally acting drugs (except an occasional hypnotic or the oral contraceptive) and who are able to be safely managed with outpatient psychotherapy.
Minimum age
16 Years
Maximum age
Not stated
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
No exclusion criteria

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Sealed envelopes.
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Computer generated permutated block randomisation
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?

Intervention assignment
Other design features
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Stopped early
Data analysis
Data analysis is complete
Reason for early stopping/withdrawal
Lack of funding/staff/facilities
Participant recruitment difficulties
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment outside Australia
Country [1] 235 0
New Zealand
State/province [1] 235 0
Christchurch, Canterbury, New Zealand

Funding & Sponsors
Funding source category [1] 1040 0
Government body
Name [1] 1040 0
Lottery Grants Board
Address [1] 1040 0
Lottery Health Research Committee
c/- Local Government and Community Branch
Department of Internal Affairs
PO Box 805
Country [1] 1040 0
New Zealand
Primary sponsor type
Government body
Lottery Grants Board
Lottery Health Research Committee
c/- Local Government and Community Branch
Department of Internal Affairs
PO Box 805
New Zealand
Secondary sponsor category [1] 902 0
Name [1] 902 0
Not applicable
Address [1] 902 0
Country [1] 902 0

Ethics approval
Ethics application status
Ethics committee name [1] 2340 0
Canterbury Ethics Committee
Ethics committee address [1] 2340 0
Ethics committee country [1] 2340 0
New Zealand
Date submitted for ethics approval [1] 2340 0
Approval date [1] 2340 0
Ethics approval number [1] 2340 0

Brief summary
Trial website
Trial related presentations / publications
Carter JD, McIntosh VV, Jordan J, Porter RJ, Frampton CM, Joyce PR. Psychotherapy for depression: A randomized clinical trial comparing schema therapy and cognitive behavior therapy. J Affect Disord. 2013;151(2):500–5.

Porter R, Bourke C, Carter J, Douglas K, McIntosh V, Jordan J, et al. No change in neuropsychological dysfunction or emotional processing during treatment of major depression with cognitive–behaviour therapy or schema therapy. Psychol Med. 2015:1-12.

Jordan J, Wilson J, Carter J, McIntosh V. Cognitive therapy and schema therapy in depression. New Zealand Clinical Psychologist Journal. 2006;16(2):19-23.
Public notes

Principal investigator
Name 36287 0
Prof Janet Carter
Address 36287 0
Psychology Department
University of Canterbury
Private Bag 4800
Christchurch 8140
Country 36287 0
New Zealand
Phone 36287 0
Fax 36287 0
+64 3 3642181
Email 36287 0
Contact person for public queries
Name 9846 0
Prof Prof Janet Carter
Address 9846 0
Psychology Department
University of Canterbury
Private Bag 4800
Christchurch 8140
Country 9846 0
New Zealand
Phone 9846 0
Fax 9846 0
+64 3 3642181
Email 9846 0
Contact person for scientific queries
Name 774 0
Prof Prof. Janet Carter
Address 774 0
Psychology Department
University of Canterbury
Private Bag 4800
Christchurch 8140
Country 774 0
New Zealand
Phone 774 0
Fax 774 0
+64 3 3642181
Email 774 0

No information has been provided regarding IPD availability
Summary results
Have study results been published in a peer-reviewed journal?
Other publications
Have study results been made publicly available in another format?
Results – basic reporting
Results – plain English summary