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Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Type of registration
Prospectively registered

Titles & IDs
Public title
The effect of taping on pain and function in people with knee osteoarthritis.
Scientific title
In persons with moderate to severe knee osteoarthritis, is McConnell patella taping more effective than a placebo in decreasing pain and improving knee kinematics during a step descent task?
Secondary ID [1] 253556 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Osteoarthritis 261116 0
Condition category
Condition code
Musculoskeletal 259263 259263 0 0

Study type
Description of intervention(s) / exposure
Participants will be randomly drawn into the taping intervention group and the vitamin E cream placebo group. McConnell taping will be applied to the subject’s knee using three strips of common sports tape, with three corresponding hypoallergenic strips of tape underlying. The patella will be pulled medially, tilted medially and rotated medially. The tape will be applied once to only one knee and for a duration of no more than 10mins in which the participant will step down from a single step for 5 repititions.
Intervention code [1] 257987 0
Treatment: Devices
Comparator / control treatment
Placebo - The vitamin E cream placebo group will have a small amount of cream briefly rubbed into their knee in the area corresponding to where the McConnell taping is applied in the intervention group. The cream will be applied to one knee only and will be briefly rubbed into the skin once immediately before repeating 5 step down repititions off a single step.
Control group

Primary outcome [1] 262080 0
Primary Outcome: Difference in knee pain between the patients no taping before intervention pain scores, with the pain scores after the tape/vitamin E cream interventions measured on a visual analogue scale (VAS-10cm).
Timepoint [1] 262080 0
Timepoint: Initial pain at baseline, then tested immediately after each step descent task. A total of five repititions with no tape for each participant, then five more repititions for either tape or cream per participant. Patients can rest for as long as needed between these repititions, but ideally if the patient is able then only 30seconds between repititions.
Secondary outcome [1] 273120 0
Secondary outcome: knee velocity, and knee range of motion of stance limb during the step descent task measured via 3D motion analysis system.
Timepoint [1] 273120 0
Timepoint: Concurrent with performing the task.

Key inclusion criteria
Aged 55-70 years, symptomatic unilateral radiographic grade 2-3 knee OA.
Minimum age
55 Years
Maximum age
70 Years
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
Lower limb surgery less than 6 months ago (excluding arthropscopic debridement and partial meniscectomy).
Systemic arthritis.
Symptomatic hip and ankle OA on the ipsilateral side.
Any clinical presentation where participation may be judged to compromise the safety of the research participant.
Known or suspected allergy to tape / elastoplast.
Isolated lateral compartment knee OA.
Diabetics with sensory neuropathy in lower limb.

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Participants will be allocated on the day by having them pick a card at random out of a sealed opaque envelopes containing cards written either taping or cream.
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Simple randomisation using computer software.
Masking / blinding
Open (masking not used)
Who is / are masked / blinded?

Intervention assignment
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Not yet recruiting
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)

Funding & Sponsors
Funding source category [1] 258441 0
Self funded/Unfunded
Name [1] 258441 0
Address [1] 258441 0
Country [1] 258441 0
Primary sponsor type
Sareen McLinton currently studying Bachelor of Physiotherapy (Honours) at the University of South Australia
University of South Australia City East campus, North Tce, Adelaide, South Australia 5000
Secondary sponsor category [1] 257587 0
Name [1] 257587 0
Dr Dominic Thewlis, Lecturer in Biomechanics at the University of South Australia and Health Science Honours student supervisor.
Address [1] 257587 0
University of South Australia City East campus, North Tce, Adelaide, South Australia 5000
Country [1] 257587 0

Ethics approval
Ethics application status
Ethics committee name [1] 260429 0
Central Northern Adelaide Health Service Ethics (CNAHS) of Human Research Committee
Ethics committee address [1] 260429 0
The Queen Elizabeth Hospital
28 Woodville Road, Woodville South, SA 5011
Ethics committee country [1] 260429 0
Date submitted for ethics approval [1] 260429 0
Approval date [1] 260429 0
Ethics approval number [1] 260429 0

Brief summary
The purpose of this study is to investigate the effect of applying sports tape to the patella in OA knees and measure whether there is a decrease in pain, and or a change in the kinematics at the knee during a step descent task. The hypothesis is that taping the patella will improve a person’s functional control of their knee, thereby decreasing the pain experienced during the task.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 32180 0
Address 32180 0
Country 32180 0
Phone 32180 0
Fax 32180 0
Email 32180 0
Contact person for public queries
Name 15427 0
Dr Dominic Thewlis BSc (Hons) PhD (Biomechanics)
Address 15427 0
University of South Australia City Each campus
North Tce Adelaide,
South Australia 5000
Country 15427 0
Phone 15427 0
+61 8 830 21540
Fax 15427 0
+61 8 830 22766
Email 15427 0
Contact person for scientific queries
Name 6355 0
Dr Dominic Thewlis BSc (Hons) PhD (Biomechanics)
Address 6355 0
University of South Australia City Each campus
North Tce Adelaide,
South Australia 5000
Country 6355 0
Phone 6355 0
+61 8 830 21540
Fax 6355 0
+61 8 830 22766
Email 6355 0

No information has been provided regarding IPD availability
Summary results
No Results