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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this information for consumers
Trial registered on ANZCTR

Registration number
Ethics application status
Date submitted
Date registered
Date last updated
Type of registration
Retrospectively registered

Titles & IDs
Public title
The Successful Treatment Of Auricular Acupuncture On Flat Warts
Scientific title
The Successful Treatment Of Auricular Acupuncture On Flat Warts
Secondary ID [1] 252338 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
flat warts(verruca plana) 257839 0
Condition category
Condition code
Skin 258005 258005 0 0
Dermatological conditions

Study type
Description of intervention(s) / exposure
weekly auricular acupuncture for 10 weeks on the ear vein located at the back of the ear, each weekly session lasts for about 1 hour
Intervention code [1] 256899 0
Treatment: Other
Comparator / control treatment
0.1 % of tretinoin ointment topically every night for 10 weeks
Control group

Primary outcome [1] 258866 0
The outcome was measured by clinical observation.The recovery rate of the treatment group was better than that of the control group (p < 0.05) and there was a significant difference in the total effective rate between the control group and the auricular acupuncture treatment group after surgery (46.66 % and 96.67 %, respectively, p < 0.01)
Timepoint [1] 258866 0
measured at baseline, and then ten weeks after treatment
Secondary outcome [1] 264991 0
The outcome was measured by clinical observation.During the treatment period, no adverse effects were observed by the investigators or reported by patients.
Timepoint [1] 264991 0
measured at baseline, and then ten weeks after treatment

Key inclusion criteria
patients aged 8 to 50 years; patients who met the clinical diagnostic criteria of flat warts; capability of providing written informed consent; and willingness and ability to comply with all procedures of the trial and attend all scheduled contacts at the investigational site.
Minimum age
8 Years
Maximum age
50 Years
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
presence of concomitant diseases which included severe allergic disease, blood disease, acute or chronic contagious disease, abnormalities in the endocrine system and scar constitution; patients having accepted other relevant therapies that might influence the results of the present study; eruption of skin lesion recently with such concomitant symptoms as severe pruritus, deepening colour or the surrounding flushes of the skin lesion; patients who dropped out halfway.

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Who is / are masked / blinded?

Intervention assignment
Other design features
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Active, not recruiting
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment outside Australia
Country [1] 2792 0
State/province [1] 2792 0

Funding & Sponsors
Funding source category [1] 257356 0
Government body
Name [1] 257356 0
research program from the Health Bureau of Shanghai
Address [1] 257356 0
No.1477, West Beijing Road,Jingan District, Shanghai,China.
Country [1] 257356 0
Primary sponsor type
Suli Ning
No.8, Caobao Rd,Shanghai,P.R.China
Secondary sponsor category [1] 256596 0
Name [1] 256596 0
Address [1] 256596 0
Country [1] 256596 0

Ethics approval
Ethics application status
Ethics committee name [1] 259376 0
Shanghai Eighth People?s Hospital
Ethics committee address [1] 259376 0
No.8, Caobao Rd, Shanghai, P.R. China
Ethics committee country [1] 259376 0
Date submitted for ethics approval [1] 259376 0
Approval date [1] 259376 0
Ethics approval number [1] 259376 0

Brief summary
Auricular acupuncture, one form of acupuncture, targets specific points on the auricle to treat various conditions. It was first reported in the mid-1950s by Nogier, but probably dates back to the Stone Age. Nogier hypothesized that all internal organs are represented in the external ear and found distinct measurable changes in the radial pulse of patients when certain points on the ear were stimulated.
The purpose of this study is to evaluate the efficacy and safety of auricular acupuncture for flat warts and to demonstrate the proper application and effective technique of this method.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 31446 0
Address 31446 0
Country 31446 0
Phone 31446 0
Fax 31446 0
Email 31446 0
Contact person for public queries
Name 14693 0
Yan Li
Address 14693 0
No. 826, Zhangheng Rd,Shanghai, P.R.China
Country 14693 0
Phone 14693 0
Fax 14693 0
Email 14693 0
Contact person for scientific queries
Name 5621 0
Yan Li
Address 5621 0
No. 826, Zhangheng Rd,Shanghai, P.R.China
Country 5621 0
Phone 5621 0
Fax 5621 0
Email 5621 0

No information has been provided regarding IPD availability
Summary results
Have study results been published in a peer-reviewed journal?
Other publications
Have study results been made publicly available in another format?
Results – basic reporting
Results – plain English summary