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Trial details imported from

For full trial details, please see the original record at

Registration number
Ethics application status
Date submitted
Date registered
Date last updated

Titles & IDs
Public title
Task-Related Training of Arm Use After Stroke
Scientific title
Task-Related Training of Arm Use After Stroke: a Randomised Controlled Trial
Secondary ID [1] 0 0
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Stroke 0 0
Condition category
Condition code
Stroke 0 0 0 0
Stroke 0 0 0 0

Study type
Description of intervention(s) / exposure
Behaviour - task-specific training

Behaviour: task-specific training

Intervention code [1] 0 0
Comparator / control treatment
Control group

Primary outcome [1] 0 0
Arm and hand function measured using the Motor Assessment Scale and the Chedoke-McMaster Impairment Inventory.
Timepoint [1] 0 0
Primary outcome [2] 0 0
Grip and pinch strength measured using dynamometers.
Timepoint [2] 0 0
Secondary outcome [1] 0 0
Dexterity measured using the NK Dexterity Board
Timepoint [1] 0 0
Secondary outcome [2] 0 0
Quality of Life measured using the Stroke-adapted Sickness Impact Profile.
Timepoint [2] 0 0
Secondary outcome [3] 0 0
Sensation using a validated assessment of tactile spatial resolution.
Timepoint [3] 0 0

Key inclusion criteria
- within 6 weeks of first stroke

- unilateral stroke

- impaired arm function

- able to cope with intensive training program

- medically stable

- able to understand instructions
Minimum age
18 Years
Maximum age
No limit
Both males and females
Can healthy volunteers participate?
Key exclusion criteria
- uncontrolled systemic disease

- significant musculotendinous or bony restrictions of the affected upper limb

- any serious chronic disease independently causing significant disability of the
affected limb

Study design
Purpose of the study
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?

Intervention assignment
Other design features
Not Applicable
Type of endpoint(s)
Statistical methods / analysis

Recruitment status
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Date of last participant enrolment
Date of last data collection
Sample size
Accrual to date
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Austin Health - Melbourne
Recruitment postcode(s) [1] 0 0
3084 - Melbourne

Funding & Sponsors
Primary sponsor type
University of Melbourne

Ethics approval
Ethics application status

Brief summary
Stroke is the leading cause of long-term physical disability in Australia. Currently around
25% of hemiplegic stroke patients discharged from rehabilitation have significantly impaired
use of the affected hand with consequent dependence in dressing, grooming and feeding
themselves. The poor outcome can be attributed in part to a lack of focus by therapists on
the negative signs of stroke (weakness and lack of dexterity) as well as too little time
(around 10 minutes per day) being devoted to retraining of the arm. Presently there is a very
limited evidence base to guide the content of clinical practice. Results from both animal and
human studies suggest that specific post-lesion training can result in substantial
improvement in function. The hypothesis is that task-specific training of the affected upper
limb to subjects in the early period following stroke will result in significantly better
functional outcome than standard intervention.
Trial website
Trial related presentations / publications
Public notes

Principal investigator
Name 0 0
Mary P Galea, PhD
Address 0 0
University of Melbourne
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries

Summary results
Other publications