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Trial registered on ANZCTR


Registration number
ACTRN12613000593730
Ethics application status
Approved
Date submitted
23/05/2013
Date registered
27/05/2013
Date last updated
27/05/2013
Type of registration
Retrospectively registered

Titles & IDs
Public title
Operating room throughput after total intravenous anesthesia with propofol compared with desflurane anesthesia in ophthalmology surgery: A retrospective comparative study
Scientific title
A retrospective comparative study to compare the anesthesia-related times that comprise a patient’s hospital stay and postoperative nausea and vomiting following ophthalmology surgery in adult patients who received different anesthesia techniques, TIVA with propofol or desflurane anesthesia.
Secondary ID [1] 282568 0
Nil
Universal Trial Number (UTN)
Trial acronym
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Efficiency of operation room following ophthalmology surgery in adult patients who received TIVA with propofol anesthesia versus desflurane anesthesia 289239 0
Condition category
Condition code
Anaesthesiology 289569 289569 0 0
Anaesthetics

Intervention/exposure
Study type
Observational
Patient registry
Target follow-up duration
Target follow-up type
Description of intervention(s) / exposure
This retrospective comparative study was compared the anesthesia-related times that comprise a patient’s hospital stay and postoperative nausea and vomiting following ophthalmology surgery in adult patients who received different anesthesia techniques, TIVA with propofol or desflurane anesthesia at Tri-Service General Hospital.
Electronic/paper medical records of all the patients were collected and reviewed from Jan. 2010 to Dec. 2011.
Intervention code [1] 287231 0
Not applicable
Comparator / control treatment
Electronic/paper medical records of all the patients who underwent ophthalmology surgery were collected and reviewed from Jan. 2010 to Dec. 2011.
Control group
Active

Outcomes
Primary outcome [1] 289664 0
The various perioperative time intervals
Timepoint [1] 289664 0
1. Anesthesia time: start of anesthesia to patient leaves operating room.
2. Surgical time: incision to surgical complete.
3. Emergence time: surgery complete to patient leaves operating room.
4. PAR stay time: the beginning of care in the PAR to discharge to the general ward.
5. Total time in operating room: start of anesthesia to discharge to the general ward. (via electronic medical records)
Secondary outcome [1] 302975 0
postoperative nausea and vomiting (PONV) and rescue for PONV
Timepoint [1] 302975 0
Within 24 hours after surgery (via paper medical records)
Secondary outcome [2] 302976 0
postoperative recovery outcomes: days in hospital
Timepoint [2] 302976 0
at least 14 days after surgery (via electronic/paper medical records)

Eligibility
Key inclusion criteria
All adult patients who underwent ophthalmology surgery at Tri-Service General Hospital and received TIVA with propofol or desflurane anesthesia from Jan. 2010 to Dec. 2011.
Minimum age
18 Years
Maximum age
80 Years
Gender
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
Patients were excluded if they met any of the following criteria: data missing, pediatric patients and patients receiving sevoflurane or propofol combined inhalation anesthesia.

Study design
Purpose
Natural history
Duration
Cross-sectional
Selection
Defined population
Timing
Retrospective
Statistical methods / analysis

Recruitment
Recruitment status
Completed
Date of first participant enrolment
Anticipated
Actual
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
Actual
Sample size
Target
Accrual to date
Final
Recruitment outside Australia
Country [1] 5102 0
Taiwan, Province Of China
State/province [1] 5102 0

Funding & Sponsors
Funding source category [1] 287342 0
Self funded/Unfunded
Name [1] 287342 0
Chueng-He Lu
Address [1] 287342 0
Department of Anesthesiology , Tri-Service General Hospital, #325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Country [1] 287342 0
Taiwan, Province Of China
Primary sponsor type
Individual
Name
Chueng-He Lu
Address
Department of Anesthesiology , Tri-Service General Hospital, #325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Country
Taiwan, Province Of China
Secondary sponsor category [1] 286092 0
None
Name [1] 286092 0
Address [1] 286092 0
Country [1] 286092 0

Ethics approval
Ethics application status
Approved
Ethics committee name [1] 289321 0
Institutional Review Board of Tri-Service General Hospital
Ethics committee address [1] 289321 0
#325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Ethics committee country [1] 289321 0
Taiwan, Province Of China
Date submitted for ethics approval [1] 289321 0
Approval date [1] 289321 0
01/09/2011
Ethics approval number [1] 289321 0
100-05-168

Summary
Brief summary
For surgical cases with general anesthesia, components of nonsurgical operating room (OR) time include induction (arrival of patient in the OR until the start of positioning), extubation (dressing on patient to extubation), and OR exit. The interval between the end of surgery and extubation (emergence time) is of special interest to anesthesia care providers and companies because it is affected by anesthetic agents. In Taiwan, a new system of Diagnosis Related Groups (DRG) has taken its part in hospital billing service since 2010. This means that the previous billing system will not be valid for current anesthesia cost in the OR any more. Instead, one sum payment one case, selection of the anesthetic technique has to be determined: cheaper agents and least possible anesthesia-controlled time to remain competitive in the operating field.
Total intravenous anesthesia (TIVA) via target controlled infusion (TCI) system incorporating the combined use of propofol and remifentanil has indeed been shown to provide more rapid emergence than other anesthesia techniques. In our previous study, we found patients undergoing prolonged procedure recover faster after TIVA than after volatile anesthesia. To evaluate potential resources for reducing time in the OR, we performed a retrospective study to compare anesthesia-related times following ophthalmology (OPH) surgery in adult patients who received different anesthesia techniques, TIVA with propofol or desflurane anesthesia.
Trial website
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 40306 0
Dr Chueng-He Lu
Address 40306 0
Department of Anesthesiology , Tri-Service General Hospital, #325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Country 40306 0
Taiwan, Province Of China
Phone 40306 0
+886-2-87927128
Fax 40306 0
Email 40306 0
box.lu@msa.hinet.net
Contact person for public queries
Name 40307 0
Dr Chueng-He Lu
Address 40307 0
Department of Anesthesiology , Tri-Service General Hospital, #325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Country 40307 0
Taiwan, Province Of China
Phone 40307 0
+886-2-87927128
Fax 40307 0
Email 40307 0
box.lu@msa.hinet.net
Contact person for scientific queries
Name 40308 0
Dr Chueng-He Lu
Address 40308 0
Department of Anesthesiology , Tri-Service General Hospital, #325, Section 2, Chenggung Road, Neihu 114, Taipei, Taiwan
Country 40308 0
Taiwan, Province Of China
Phone 40308 0
+886-2-87927128
Fax 40308 0
Email 40308 0
box.lu@msa.hinet.net

No information has been provided regarding IPD availability
Summary results
Have study results been published in a peer-reviewed journal?
Other publications
Have study results been made publicly available in another format?
Results – basic reporting
Results – plain English summary