December 2017: The clinical trials landscape in Australia 2006-2015
ANZCTR staff are delighted to share with you our recently published report entitled:
"The clinical trials landscape in Australia 2006-2015". To view the report, please click here.
November 2017: Article published in NEJM: Data Sharing from Clinical Trials — A Research Funder’s Perspective
Link to article in the New England Journal of Medicine. View here.
June 2016: Changes to recruitment statuses on the ANZCTR
Details of these changes can be viewed here.
July 2015: Article published in MJA: Australian clinical trial activity and burden of disease:
an analysis of registered trials in National Health Priority Areas
Link to article in the Medical Journal of Australia. View here
Link to commentary in MJA InSight. View here
View our newsletters here.
(www.australianclinicaltrials.gov.au) sees clinical trial doors open for patients
Link to article in The Australian. View here
Link to Joint Media Release by Minister for Health Sussan Ley and Minister for Industry
and Science Ian Macfarlane.
The ANZCTR registers its 10,000th trial
This major milestone was reached in November 2014. More...
Registration as a tool to increase research value
This article, published in the Lancet, advocates trial registration as a
tool to increase research value. More...
Trial registration now a condition for ethical approval in the UK
Ian Chalmers discusses this significant milestone in his BMJ editorial. More...
An international movement to boost transparency in clinical trials is gathering
momentum. Iain Chalmers, who has championed these issues for many years, talks to
Fiona Fleck. More...
Registration requirement for project grant applications
As announced in section 6.3 of the "NHMRC Project Grants Funding Policy" for 2012,
all NHMRC funded clinical trials must be registered in the Australian New Zealand
Clinical Trials Registry (ANZCTR), or equivalent, prior to commencement of the clinical
Australian Cancer Trials
The Australian Cancer Trials website (http://www.australiancancertrials.gov.au/) was launched
in November 2010, containing information on cancer clinical trials with a recruitment
site in Australia, uploaded on a regular basis from the ANZCTR and ClinicalTrials.gov
databases. The website is designed for and aimed towards the Australian consumer,
by making clinical trials information more accessible for patients and their healthcare
teams, and also in helping facilitate participation in these studies.
Articles of interest
Unreported trials a betrayal of patients.
BMJ Editorial: All trials must be registered and the results published.
Biggest cancer killers lack adequate research
to clinical trial registries: insights from Australian Cancer Trials Online, a website
Landscape of cancer clinical trials in Australia: using trial registries to guide
Quality of Registration of Clinical Trials
Trials registration now part of the revised CONSORT statement
ANZCTR has met the requirements of the ICMJE's trials registration policy and is
now an ICMJE acceptable registry. More...
Issues in the Registration of Clinical Trials [JAMA 297(19); 2112-2120, 2007] More...
US legislation developments: In March 2007, US Congress Representatives Henry A.
Waxman and Edward J. Markey introduced counterpart legislation to the Enzi-Kennedy
US Senate bill which intends to further enhance the proposed mandatory clinical
trial registry and results database. More...
WHO establishes an International Clinical Trials Registry Platform (ICTRP)
The World Health Organisation (WHO) held a consensus meeting in New York in October
2004 that brought together government research institutions, pharmaceutical industry
representatives, journal editors, researchers, and other leading experts to identify
substantial common ground regarding trial registration. A general consensus was
reached regarding the need for worldwide clinical trial registration. The so called
"New York Statement 2004" noted the following:
The need for a global approach to clinical trials registration
- Trials unambiguously identified
- Consensus needed on which trials; data; timing and disclosure of results
- One-stop search portal; publicly available
- System is simple, effective, efficient
- Capacity built where appropriate
The ICTRP can be accessed via:
www.who.int/ictrp/en/ to develop an international, electronic search portal
through which registries around the world can be located and accessed. This search portal became functional in May 2007. A second objective
of the ICTRP is to establish processes for recognising registers of certain standards
as Primary Registers. There are also plans for the development of a worldwide unique
trial ID numbering system.